<dfn id="w48us"></dfn><ul id="w48us"></ul>
  • <ul id="w48us"></ul>
  • <del id="w48us"></del>
    <ul id="w48us"></ul>
  • 抗原特異性免疫治療對花粉癥的長期療效

    時間:2024-09-15 10:50:26 藥學(xué)畢業(yè)論文 我要投稿
    • 相關(guān)推薦

    抗原特異性免疫治療對花粉癥的長期療效

    作者:林小平,何韶衡,高軍,遲秀麗
    【關(guān)鍵詞】 表位
    Longterm effect evaluation of antigen specific immunotherapy for patients with pollen allergy
      【Abstract】 AIM: To evaluate the effectiveness of allergen specific immunotherapy (SIT) in treating patients with pollinosis. METHODS: A total of 235 patients with pollen allergy were recruited into the study and were randomly divided into two groups: SIT group with subgroups: allergic rhinitis group (n=65) and allergic rhinitis asthma group (n=60), and ST (symptomatic therapy) group with subgroups: allergic rhinitis group (n=56) and allergic rhinitis asthma group (n=54). Fortythree healthy individuals were taken as controls. The levels of serum total IgE (tIgE), specific IgE (sIgE) and eosinophil cantionic protein (ECP) were determined with Uni CAP system. IgG was measured and eosinophil numbers were counted. The abovementioned indices, lung function indices, symptomatic score and skin test results were compared between the two groups before and after treatment. RESULTS: The elevated levels of tIgE, sIgE, ECP and tIgE: IgG in the sera and eosinophil counts in peripheral blood of the patients were significantly reduced, whereas the level of IgG increased following treatment with SIT. Lung function, symptomatic score and skin test result all improved after the treatment with SIT. Approximately 40% of the patients were clinically cured and 57.7% responded to SIT. Only 2.3% remained unchanged and about 8.9% patients suffered side effects of SIT. No changes in the abovementioned indices were observed in ST group. CONCLUSION: SIT can improve the symptoms of the patients with allergic rhinitis and asthma by increasing the level of serum IgG, decreasing the IgE and inhibiting the eosinophil counts in peripheral blood.
      【Keywords】 epitopes; immunotherapy; hay fever; Immunoglobulin E (IgE)
      【摘要】 目的: 探討抗原特異性免疫治療(specific immunotherapy, SIT)對花粉癥患者的療效及作用機制. 方法: 選擇對夏秋季豚草(Ragweed)和蒿草(Atremisa vulgaris)過敏的花粉癥患者(過敏性鼻炎或哮喘)235例,隨機分為SIT組:包括過敏性鼻炎組(n=65);過敏性鼻炎 哮喘組(n=60);對癥治療組(symptomatic therapy, ST),同樣包括過敏性鼻炎組(n=56),和過敏性鼻炎 哮喘組(n=54). 健康對照組(n=43). 應(yīng)用UniCAPsystem免疫熒光法、雙抗體夾心ELISA法、放射比濁法和瑞氏染色法分別測定血清特異性IgE(sIgE)、總IgE(tIgE)、嗜酸性粒細胞陽離子蛋白(ECP)、IgG水平和外周血嗜酸性粒細胞(Eos)計數(shù). 分別比較二組治療前、后上述各種參數(shù)、肺功能指標(biāo)、癥狀評分和皮膚試驗指數(shù)的變化. 結(jié)果: 治療前,患者血清sIgE、tIgE、ECP水平、血Eos計數(shù)、tIgE: IgG值均明顯升高(P

    【抗原特異性免疫治療對花粉癥的長期療效】相關(guān)文章:

    神經(jīng)癥患者人性化護理療效分析論文07-01

    鹽酸氟西汀治療21例強迫癥的療效觀察09-03

    長期臥床病人的并發(fā)癥預(yù)防和護理06-20

    談腰椎間盤突出癥臭氧治療與保守治療的療效比較10-30

    減重步行訓(xùn)練對卒中后遺癥期偏癱患者的康復(fù)療效09-02

    繼發(fā)孔型房間隔缺損介入治療效果及并發(fā)癥觀察09-15

    伽瑪?shù)吨委熑嫔窠?jīng)鞘瘤的長期療效分析及心理護理09-06

    奎的平與氯氮平治療精神分裂癥療效比較研究05-25

    MED術(shù)治療青少年腰椎間盤突出癥41例療效分析10-23

    110例康復(fù)期精神分裂癥患者心理護理療效觀察10-27

    主站蜘蛛池模板: 亚洲精品国产字幕久久不卡| 久久永久免费人妻精品下载| 伊人精品久久久久7777| 国产精品欧美久久久天天影视| 欧美精品区一级片免费播放| 好吊妞视频精品| 精品不卡一区二区| 无码精品A∨在线观看中文| 久久精品一区二区影院| 97久久精品人人澡人人爽| 91精品国产91久久久久福利| 亚洲中文久久精品无码| 无码8090精品久久一区| 国精品无码A区一区二区| 99精品视频在线观看婷| 国产精品久久久久久| 国产精品亚洲аv无码播放| 无码国内精品久久人妻| 亚洲欧美日韩另类精品一区二区三区| 国产伦精品一区二区三区视频猫咪| 欧美日韩精品乱国产538| 国产精品成人va| 国产成人无码精品一区二区三区| 无码精品国产VA在线观看 | 亚洲国产精品无码中文字| 久久精品成人影院| 精品无码国产自产拍在线观看蜜| 国产欧美在线观看精品一区二区| 国产情侣大量精品视频| 国内精品视频九九九九| 国产精品综合久成人| 精品国产爽爽AV| 久久久久亚洲精品天堂久久久久久 | 国产视频精品免费视频| 精品91自产拍在线观看| 国精品产露脸自拍| 久热精品人妻视频| 亚洲精品视频在线看| 亚洲综合国产精品第一页| 亚洲国产精品无码一线岛国| 久久精品aⅴ无码中文字字幕重口 久久精品a亚洲国产v高清不卡 |